The pick of the 2nd leg games was Independiente's 4-2 win against Uruguayan side Defensor Sporting Club, which was selected as our game of the week.
There were plenty of other brilliant games. Colombian side Deportes Tolima overturned a 2 goal defecit against Banfield with a 3-0 win, Brazilian side Avai scored 3 goals to win their game against Emelec from 1-3 down on aggregate and Uruguyan side Peñarol were eliminated on away goals after an entertaining 3-2 win against Brazilian side Goiás.
Brazilian sides dominate the quarter final line up with 4 representatives, there are 2 Argentine teams and one each from Colombia and Ecuador.
|Defensor Sporting (Uru)||1-0||Independiente (Arg)|
|Independiente (Arg)||4-2||Defensor Sporting (Uru)|
|Banfield (Arg)||2-0||Deportes Tolima (Col)|
|Deportes Tolima (Col)||3-0||Banfield (Arg)|
|Winner: Deportes Tolima|
|Newell's Old Boys (Arg)||6-0||San José (Bol)|
|San José (Bol)||2-0||Newell's Old Boys (Arg)|
|Winner: Newell's Old Boys|
|Unión San Felipe (Chi)||4-2||LDU Quito (Ecu)|
|LDU Quito (Ecu)||6-1||Unión San Felipe (Chi)|
|Winner: LDU Quito|
|Goiás (Bra)||1-0||Peñarol (Uru)|
|Peñarol (Uru)||3-2||Goiás (Bra)|
|Winner: Goiás (on away goals)|
|Atlético MG (Bra)||2-0||Independiente Santa Fe (Col)|
|Independiente Santa Fe (Col)||1-0||Atlético MG (Bra)|
|Winner: Atlético MG|
|Emelec (Ecu)||2-1||Avai (Bra)|
|Avai (Bra)||3-1||Emelec (Ecu)|
|Universitario (Bol)||0-1||Palmeiras (Bra)|
|Palmeiras (Bra)||3-1||Universitario (Bol)|